Endocrine Abstracts

Background and aim: Chronic Kidney Disease and Diabetes Mellitus can influenceCoronary Artery Disease (CAD) independently. The aim of this study was to evaluate the association of Glomerular Filtration Rate (GFR) and Coronary Artery Disease in type 2 diabetic patients. (T2DM)Methods: This cross sectional study evaluated 362 T2DM patients with clinical presentation of CAD whose documents were registered in angiography center during 18 months. GFR was meas...

Background: Obesity, particularly abdominal obesity, is associated with resistance to the effects of insulin on peripheral glucose and fatty acid utilization, often leading to type 2 diabetes mellitus. Insulin resistance, the associated hyperinsulinemia and hyperglycemia, and adipocyte cytokines (adipokines) may also lead to vascular endothelial dysfunction, an abnormal lipid profile, hypertension, and vascular inflammation, all of which promote the development of atherosclero...